Vladimir Kiradjiev has developed from being the director of various symphony orchestras and ensembles for contemporary music to being one of the most sought-after opera conductors in Central and Eastern Europe. After graduating from the State Academy of Music in Sofia, Vladimir Kiradjiev continued his studies with Kurt Masur (in Leipzig), Franco Ferrara (in Siena) and Karl Österreicher (in Vienna). In 1984 he became Artistic Director of the Opera in Sliven and also the permanent guest conductor of almost all the philharmonic orchestras in Bulgaria. In 1990 he relocated to Vienna and became principal conductor of the Vienna Residence Orchestra.

Vladimir Kiradjiev is permanent guest conductor at numerous opera houses, including Stadttheater Luzern, Deutsche Oper Berlin, Komische Oper Berlin, Berlin Metropol Theater, Latvian National Opera in Riga, National Opera of Bulgaria in Sofia, Tatar State Academic Opera in Kazan, and Krakow Opera in Poland. He has conducted orchestras throughout Europe, as well as in Mexico, Colombia, South Korea and China, and has collaborated with soloists including Anna Netrebko, Elīna Garanča, Maija Koval,evska, Matti Salminen, Marcelo Álvarez, Rafał Blechacz, and many others.

From 2008 to 2013 Vladimir Kiradjiev was Artistic Director of the Filharmonia Podkarpacka in Rzeszów, Poland, and Artistic Director of the Music Festival in Łan´cut, Poland. Since 2013–14 he has been first guest conductor at Opera na Zamku in Szczecin, also in Poland. Mr Kiradjiev teaches at the Institute for Conducting at the University of Music and Performing Arts in Vienna.